I'm always on Facebook and Twitter -- I love staying in touch with my folks, loved ones and my TP friends. And HTC Sense's FriendStream app makes my social networking experience even more enjoyable.
Here's a video that I recently recorded showing the neat features of FriendStream Widget and Application --
FriendStream running on my HTC Desire HD
What's really nice about it is that it's very neat and organized, and it shows all of the updates from your friends in just one location -- so you don't have to jump from one app to another to not miss out on anything.